High-throughput liquid chromatography tandem mass spectrometry method for simultaneous determination of fampridine, paroxetine, and quinidine in rat plasma: Application to in vivo perfusion study

A selective and high-throughput liquid chromatography–mass spectrometry method has been developed and validated for the simultaneous quantification of paroxetine, fampridine, and quinidine in rat plasma using imipramine as an internal standard. Following protein precipitation extraction, the analyte...

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Bibliographic Details
Main Authors: Suneetha Achanti, Raja Rajeswari Katta
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Journal of Food and Drug Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949816300321