A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture.

Exposure to toxaphene, an environmentally persistent mixture of chlorinated terpenes previously utilized as an insecticide, has been associated with various cancers and diseases such as amyotrophic lateral sclerosis. Nevertheless, the cellular and molecular mechanisms responsible for these toxic eff...

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Bibliographic Details
Main Authors: Brandon D Gaytán, Alex V Loguinov, Xenia Peñate, Jan-Michael Lerot, Sebastián Chávez, Nancy D Denslow, Chris D Vulpe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832591?pdf=render