TREM2 in Neurodegenerative Diseases

TREM2 in Neurodegenerative Diseases

Abstract TREM2 variants have been identified as risk factors for Alzheimer’s disease (AD) and other neurodegenerative diseases (NDDs). Because TREM2 encodes a receptor exclusively expressed on immune cells, identification of these variants conclusively demonstrates that the immune response can play...

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Bibliographic Details
Main Authors: Taylor R. Jay, Victoria E. von Saucken, Gary E. Landreth
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Molecular Neurodegeneration
Subjects:
Microglia
Inflammation
Genetics
Genetic risk factors
Neurodegeneration
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s13024-017-0197-5

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