Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

Abstract Background Advances in automated image-based microscopy platforms coupled with high-throughput liquid workflows have facilitated the design of large-scale screens utilising multicellular model organisms such as Caenorhabditis elegans to identify genetic interactions, therapeutic drugs or di...

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Bibliographic Details
Main Authors: Blanca Hernando-Rodríguez, Annmary Paul Erinjeri, María Jesús Rodríguez-Palero, Val Millar, Sara González-Hernández, María Olmedo, Bettina Schulze, Ralf Baumeister, Manuel J. Muñoz, Peter Askjaer, Marta Artal-Sanz
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Biology
Subjects:
C. elegans
Essential genes
Worm sorting
Image analysis
High-content
High-throughput
Online Access:http://link.springer.com/article/10.1186/s12915-018-0496-5

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