RNA Signaling in Pulmonary Arterial Hypertension—A Double-Stranded Sword

RNA Signaling in Pulmonary Arterial Hypertension—A Double-Stranded Sword

Recognition of and response to pathogens and tissue injury is driven by the innate immune system via activation of pattern recognition receptors. One of the many patterns recognized is RNA and, while several receptors bind RNA, Toll-like receptor 3 (TLR3) is well placed for initial recognition of RN...

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Bibliographic Details
Main Authors: Helena A. Turton, A. A. Roger Thompson, Laszlo Farkas
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
pulmonary arterial hypertension
Toll-like receptor
TLR3
double-stranded RNA
RNA sensors
vascular remodeling
Online Access:https://www.mdpi.com/1422-0067/21/9/3124

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