Chronic post-traumatic osteomyelitis as a problem of contemporary traumatology and orthopedics (literature review)

• Main Authors: Sergei P. Mironov, Archil V. Tsiskarashvili, Dmitrii S. Gorbatiuk
• Format: Article
• Language: English
• Published: Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics 2019-12-01
• Series: Гений oртопедии
• Subjects: chronic osteomyelitis; antibiotic therapy; resistance of microorganisms; inflammation; biochemical cascade; microbial biofilms; bone tissue infectious process; persistent cells; chronic osteomyelitis pathomorphology; osteoblast; osteoclast; staphylococcus aureus; immunology
• Online Access: http://ilizarov-journal.com/files/eng/2019_4_24_Eng.pdf
• ISSN: 1028-4427; 2542-131X

The paper discusses the problem of chronic osteomyelitis from the positions that are either circumvented or not taken into account by practitioners. Microbiological, clinical, pharmacological, pathomorphological and pathophysiological aspects of the inflammatory process of bone tissue are presented. The review also outlines the immunological features of the chronic osteomyelitis course, as well as a contemporary view on this disease as an interdisciplinary problem.