2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence...
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doaj-7328a2debbe5415ba8400ae38abca9ec2021-07-15T15:36:43ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-06-01226771677110.3390/ijms221367712021 Update on Diagnostic Markers and Translocation in Salivary Gland TumorsMalin Tordis Meyer0Christoph Watermann1Thomas Dreyer2Süleyman Ergün3Srikanth Karnati4Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, GermanyDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, GermanyInstitute for Pathology, Justus Liebig University, Langhansstrasse 10, 35392 Gießen, GermanyInstitute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, GermanyInstitute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, GermanySalivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.https://www.mdpi.com/1422-0067/22/13/6771salivary gland tumorsepithelial salivary glandadenoid cystic carcinoma (ACC)pleomorphic adenomamucoepidermoid carcinomadiagnostic markers |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Malin Tordis Meyer Christoph Watermann Thomas Dreyer Süleyman Ergün Srikanth Karnati |
spellingShingle |
Malin Tordis Meyer Christoph Watermann Thomas Dreyer Süleyman Ergün Srikanth Karnati 2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors International Journal of Molecular Sciences salivary gland tumors epithelial salivary gland adenoid cystic carcinoma (ACC) pleomorphic adenoma mucoepidermoid carcinoma diagnostic markers |
author_facet |
Malin Tordis Meyer Christoph Watermann Thomas Dreyer Süleyman Ergün Srikanth Karnati |
author_sort |
Malin Tordis Meyer |
title |
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors |
title_short |
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors |
title_full |
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors |
title_fullStr |
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors |
title_full_unstemmed |
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors |
title_sort |
2021 update on diagnostic markers and translocation in salivary gland tumors |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1661-6596 1422-0067 |
publishDate |
2021-06-01 |
description |
Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors. |
topic |
salivary gland tumors epithelial salivary gland adenoid cystic carcinoma (ACC) pleomorphic adenoma mucoepidermoid carcinoma diagnostic markers |
url |
https://www.mdpi.com/1422-0067/22/13/6771 |
work_keys_str_mv |
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