2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors

Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence...

Full description

Bibliographic Details
Main Authors: Malin Tordis Meyer, Christoph Watermann, Thomas Dreyer, Süleyman Ergün, Srikanth Karnati
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/13/6771
id doaj-7328a2debbe5415ba8400ae38abca9ec
record_format Article
spelling doaj-7328a2debbe5415ba8400ae38abca9ec2021-07-15T15:36:43ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-06-01226771677110.3390/ijms221367712021 Update on Diagnostic Markers and Translocation in Salivary Gland TumorsMalin Tordis Meyer0Christoph Watermann1Thomas Dreyer2Süleyman Ergün3Srikanth Karnati4Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, GermanyDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, GermanyInstitute for Pathology, Justus Liebig University, Langhansstrasse 10, 35392 Gießen, GermanyInstitute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, GermanyInstitute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, GermanySalivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.https://www.mdpi.com/1422-0067/22/13/6771salivary gland tumorsepithelial salivary glandadenoid cystic carcinoma (ACC)pleomorphic adenomamucoepidermoid carcinomadiagnostic markers
collection DOAJ
language English
format Article
sources DOAJ
author Malin Tordis Meyer
Christoph Watermann
Thomas Dreyer
Süleyman Ergün
Srikanth Karnati
spellingShingle Malin Tordis Meyer
Christoph Watermann
Thomas Dreyer
Süleyman Ergün
Srikanth Karnati
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
International Journal of Molecular Sciences
salivary gland tumors
epithelial salivary gland
adenoid cystic carcinoma (ACC)
pleomorphic adenoma
mucoepidermoid carcinoma
diagnostic markers
author_facet Malin Tordis Meyer
Christoph Watermann
Thomas Dreyer
Süleyman Ergün
Srikanth Karnati
author_sort Malin Tordis Meyer
title 2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
title_short 2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
title_full 2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
title_fullStr 2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
title_full_unstemmed 2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
title_sort 2021 update on diagnostic markers and translocation in salivary gland tumors
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1661-6596
1422-0067
publishDate 2021-06-01
description Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.
topic salivary gland tumors
epithelial salivary gland
adenoid cystic carcinoma (ACC)
pleomorphic adenoma
mucoepidermoid carcinoma
diagnostic markers
url https://www.mdpi.com/1422-0067/22/13/6771
work_keys_str_mv AT malintordismeyer 2021updateondiagnosticmarkersandtranslocationinsalivaryglandtumors
AT christophwatermann 2021updateondiagnosticmarkersandtranslocationinsalivaryglandtumors
AT thomasdreyer 2021updateondiagnosticmarkersandtranslocationinsalivaryglandtumors
AT suleymanergun 2021updateondiagnosticmarkersandtranslocationinsalivaryglandtumors
AT srikanthkarnati 2021updateondiagnosticmarkersandtranslocationinsalivaryglandtumors
_version_ 1721299336819638272