GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis

GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis

Abstract Frameshift mutations frequently occur in colorectal cancer (CRC) with microsatellite instability (MSI), but the nature and biological function of many MSI‐associated mutations remain elusive. Here, an MSI frameshift mutation is identified in glioma tumor suppressor candidate region gene 1 (...

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Bibliographic Details
Main Authors: Fengyan Han, Lei Zhang, Chaoyi Chen, Yan Wang, Yi Zhang, Lili Qian, Wenjie Sun, Dan Zhou, Beibei Yang, Honghe Zhang, Maode Lai
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Advanced Science
Subjects:
frameshift mutations
glioma tumor suppressor candidate region gene 1 (GLTSCR1)
microsatellite instability (MSI)
transcription elongation
Online Access:https://doi.org/10.1002/advs.201901114

Internet

https://doi.org/10.1002/advs.201901114

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