ANOVA-like differential expression (ALDEx) analysis for mixed population RNA-Seq.

ANOVA-like differential expression (ALDEx) analysis for mixed population RNA-Seq.

Experimental variance is a major challenge when dealing with high-throughput sequencing data. This variance has several sources: sampling replication, technical replication, variability within biological conditions, and variability between biological conditions. The high per-sample cost of RNA-Seq o...

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Bibliographic Details
Main Authors: Andrew D Fernandes, Jean M Macklaim, Thomas G Linn, Gregor Reid, Gregory B Gloor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699591?pdf=render

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