Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C.

Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C.

Genome-wide association studies (GWAS) have revealed many single nucleotide polymorphisms (SNPs) associated with complex traits. Although these studies frequently fail to identify statistically significant associations, the top association signals from GWAS may be enriched for true associations. We...

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Bibliographic Details
Main Authors: Joanna M Biernacka, Jennifer R Geske, Terry D Schneekloth, Mark A Frye, Julie M Cunningham, Doo-Sup Choi, Courtney L Tapp, Bradley R Lewis, Maureen S Drews, Tracy L Pietrzak, Colin L Colby, Daniel K Hall-Flavin, Larissa L Loukianova, John A Heit, David A Mrazek, Victor M Karpyak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596339?pdf=render

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