A nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malaria.

A nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malaria.

Trials testing the RTS,S candidate malaria vaccine and radiation-attenuated sporozoites (RAS) have shown that protective immunity against malaria can be induced and that an effective vaccine is not out of reach. However, longer-term protection and higher protection rates are required to eradicate ma...

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Bibliographic Details
Main Authors: Frédéric Coutant, Raul Yusef Sanchez David, Tristan Félix, Aude Boulay, Laxmee Caleechurn, Philippe Souque, Catherine Thouvenot, Catherine Bourgouin, Anne-Sophie Beignon, Pierre Charneau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3487763?pdf=render

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