Enhancing the Protective Immune Response to Administration of a LIVP-GFP Live Attenuated Vaccinia Virus to Mice

Enhancing the Protective Immune Response to Administration of a LIVP-GFP Live Attenuated Vaccinia Virus to Mice

Following the WHO announcement of smallpox eradication, discontinuation of smallpox vaccination with vaccinia virus (VACV) was recommended. However, interest in VACV was soon renewed due to the opportunity of genetic engineering of the viral genome by directed insertion of foreign genes or introduct...

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Bibliographic Details
Main Authors: Sergei N. Shchelkunov, Stanislav N. Yakubitskiy, Kseniya A. Titova, Stepan A. Pyankov, Alexander A. Sergeev
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pathogens
Subjects:
poxviruses
vaccinia virus
vaccines
immune response
antibodies
protection
Online Access:https://www.mdpi.com/2076-0817/10/3/377

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