Gene silencing of Toll-like receptor 2 inhibits proliferation of human liver cancer cells and secretion of inflammatory cytokines.

BACKGROUND: Toll-like receptors (TLRs) are key factors in the innate immune system and initiate the inflammatory response to foreign pathogens such as bacteria, fungi and viruses. In the microenvironment of tumorigenesis, TLRs can promote inflammation and cell survival. Toll-like receptor 2/6 (TLR2/...

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Bibliographic Details
Main Authors: Yuzheng Huang, Bing Cai, Ming Xu, Zhiqin Qiu, Yonghui Tao, Ying Zhang, Jie Wang, Yongliang Xu, Yonghua Zhou, Jing Yang, Xiaofeng Han, Qi Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398009?pdf=render