Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells
Abstract Background Fibrinogen is a central player in the blood coagulation cascade and one of the most abundant plasma proteins. This glycoprotein also triggers important events (e.g., cell spreading, the respiratory burst and degranulation) in neutrophil cells via a αMβ2 integrin-mediated binding...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12967-018-1446-2 |