Embryotoxic and Teratogenic Effects of Nickel in Swiss Albino Mice during Organogenetic Period

The present study evaluates potential hazardous of nickel (Ni+2 as NiCl2·6H2O) to Swiss albino mice fetus. Ni was administered orally on body weight base from days 6 to 13 of gestation period. Based on LD50, Ni doses (46.125, 92.25, and 184.5) mg Ni/kg b.wt. were used. On day 18 of gestation, uteri...

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Bibliographic Details
Main Authors: Shivi Saini, Neena Nair, Mali Ram Saini
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/701439