Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.
Main Authors: | S. Rempel, E. Colucci, J. W. de Gier, A. Guskov, D. J. Slotboom |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05441-9 |
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