Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM

Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM

Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.

Bibliographic Details
Main Authors: S. Rempel, E. Colucci, J. W. de Gier, A. Guskov, D. J. Slotboom
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05441-9
id doaj-72fc0697a8c449729feb9bbe1e3643d9
record_format Article
spelling doaj-72fc0697a8c449729feb9bbe1e3643d92021-05-11T10:14:41ZengNature Publishing GroupNature Communications2041-17232018-08-01911810.1038/s41467-018-05441-9Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuMS. Rempel0E. Colucci1J. W. de Gier2A. Guskov3D. J. Slotboom4Groningen Biomolecular and Biotechnology Institute (GBB), University of GroningenGroningen Biomolecular and Biotechnology Institute (GBB), University of GroningenDepartment of Biochemistry and Biophysics, Stockholm UniversityGroningen Biomolecular and Biotechnology Institute (GBB), University of GroningenGroningen Biomolecular and Biotechnology Institute (GBB), University of GroningenUptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.https://doi.org/10.1038/s41467-018-05441-9
collection DOAJ
language English
format Article
sources DOAJ
author S. Rempel
E. Colucci
J. W. de Gier
A. Guskov
D. J. Slotboom
spellingShingle S. Rempel
E. Colucci
J. W. de Gier
A. Guskov
D. J. Slotboom
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
Nature Communications
author_facet S. Rempel
E. Colucci
J. W. de Gier
A. Guskov
D. J. Slotboom
author_sort S. Rempel
title Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_short Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_full Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_fullStr Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_full_unstemmed Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
title_sort cysteine-mediated decyanation of vitamin b12 by the predicted membrane transporter btum
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-08-01
description Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.
url https://doi.org/10.1038/s41467-018-05441-9
work_keys_str_mv AT srempel cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum
AT ecolucci cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum
AT jwdegier cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum
AT aguskov cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum
AT djslotboom cysteinemediateddecyanationofvitaminb12bythepredictedmembranetransporterbtum
_version_ 1721448511682117632

Similar Items