CD28 between tolerance and autoimmunity: the side effects of animal models [version 1; referees: 2 approved]
Regulation of immune responses is critical for ensuring pathogen clearance and for preventing reaction against self-antigens. Failure or breakdown of immunological tolerance results in autoimmunity. CD28 is an important co-stimulatory receptor expressed on T cells that, upon specific ligand binding,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2018-05-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/7-682/v1 |