Transcriptome Profiling and Molecular Therapeutic Advances in Cystic Fibrosis: Recent Insights

Transcriptome Profiling and Molecular Therapeutic Advances in Cystic Fibrosis: Recent Insights

In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (<i>CFTR</i>) gene disrupt the capacity of the encoded protein to function as a channel to transport chloride ions and water across cell membranes. The consequences are deleterious, system-wide,...

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Bibliographic Details
Main Authors: Justin E. Ideozu, Xi Zhang, Susanna McColley, Hara Levy
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Genes
Subjects:
cystic fibrosis
transcriptome profiling
molecular therapy
RNA-Seq
microarray
Online Access:https://www.mdpi.com/2073-4425/10/3/180

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