The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons

The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons

The polymorphisms of MC1R gene play a crucial role in coat color variation in mammals; however, the relationship is still unclear in pigeons. In this study, we sequenced 741 bp fragment of the MC1R for 39 individuals with five plumage color patterns (gray plumage, n=12; black plumage, n=9; white plu...

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Main Authors: Jin-Shan Ran, Xiao-Yan You, Jie Jin, Yu-Guang Zhou, Ye Wang, Dan Lan, Peng Ren, Yi-Ping Liu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/3059756
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spelling doaj-72eef89a62924242a4cf27c7e54c95592020-11-24T23:51:08ZengHindawi LimitedBioMed Research International2314-61332314-61412016-01-01201610.1155/2016/30597563059756The Relationship between MC1R Mutation and Plumage Color Variation in PigeonsJin-Shan Ran0Xiao-Yan You1Jie Jin2Yu-Guang Zhou3Ye Wang4Dan Lan5Peng Ren6Yi-Ping Liu7Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaChongqing Academy of Animal Science, Rongchang, Chongqing 402460, ChinaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, ChinaThe polymorphisms of MC1R gene play a crucial role in coat color variation in mammals; however, the relationship is still unclear in pigeons. In this study, we sequenced 741 bp fragment of the MC1R for 39 individuals with five plumage color patterns (gray plumage, n=12; black plumage, n=9; white plumage, n=3; spotted plumage, n=12; red plumage, n=3). A total of three single nucleotide polymorphisms (SNPs) were detected, including G199A, G225A, and A466G, which subsequently determined four haplotypes (H1–H4). Among them, H1 is the predominant haplotype. Association analysis revealed that H1 and H3 were significantly associated with the black plumage trait (P<0.05), while the H4 was significantly associated with gray plumage trait (P<0.05). Furthermore, only diplotype H1H1 was significantly associated with black and gray traits of pigeons. Collectively, our study suggested an association between genetic variation of MC1R and plumage color in pigeon.http://dx.doi.org/10.1155/2016/3059756
collection DOAJ
language English
format Article
sources DOAJ
author Jin-Shan Ran
Xiao-Yan You
Jie Jin
Yu-Guang Zhou
Ye Wang
Dan Lan
Peng Ren
Yi-Ping Liu
spellingShingle Jin-Shan Ran
Xiao-Yan You
Jie Jin
Yu-Guang Zhou
Ye Wang
Dan Lan
Peng Ren
Yi-Ping Liu
The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons
BioMed Research International
author_facet Jin-Shan Ran
Xiao-Yan You
Jie Jin
Yu-Guang Zhou
Ye Wang
Dan Lan
Peng Ren
Yi-Ping Liu
author_sort Jin-Shan Ran
title The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons
title_short The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons
title_full The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons
title_fullStr The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons
title_full_unstemmed The Relationship between MC1R Mutation and Plumage Color Variation in Pigeons
title_sort relationship between mc1r mutation and plumage color variation in pigeons
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2016-01-01
description The polymorphisms of MC1R gene play a crucial role in coat color variation in mammals; however, the relationship is still unclear in pigeons. In this study, we sequenced 741 bp fragment of the MC1R for 39 individuals with five plumage color patterns (gray plumage, n=12; black plumage, n=9; white plumage, n=3; spotted plumage, n=12; red plumage, n=3). A total of three single nucleotide polymorphisms (SNPs) were detected, including G199A, G225A, and A466G, which subsequently determined four haplotypes (H1–H4). Among them, H1 is the predominant haplotype. Association analysis revealed that H1 and H3 were significantly associated with the black plumage trait (P<0.05), while the H4 was significantly associated with gray plumage trait (P<0.05). Furthermore, only diplotype H1H1 was significantly associated with black and gray traits of pigeons. Collectively, our study suggested an association between genetic variation of MC1R and plumage color in pigeon.
url http://dx.doi.org/10.1155/2016/3059756
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