An albumin-derived peptide scaffold capable of binding and catalysis.

An albumin-derived peptide scaffold capable of binding and catalysis.

We have identified a 101-amino-acid polypeptide derived from the sequence of the IIA binding site of human albumin. The polypeptide contains residues that make contact with IIA ligands in the parent protein, and eight cysteine residues to form disulfide bridges, that stabilize the polypeptide struct...

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Bibliographic Details
Main Authors: Immacolata Luisi, Silvia Pavan, Giampaolo Fontanive, Alessandro Tossi, Fabio Benedetti, Adriano Savoini, Elisa Maurizio, Riccardo Sgarra, Daniele Sblattero, Federico Berti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579865?pdf=render

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