IN VITRO IMMUNOTROPICITY STUDIES OF POLYFUNCTIONAL WATER-SOLUBLE ANTIOXIDANTS

IN VITRO IMMUNOTROPICITY STUDIES OF POLYFUNCTIONAL WATER-SOLUBLE ANTIOXIDANTS

Abstract. A study of immunotropic properties of ω-(3,5-dimethyl-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-11-7), and ω-(3,5-di-tret-butil-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-17-7) was carried out, employing an in vitro model of spontaneous and mitogen- stimulated prolifer...

Full description

Bibliographic Details
Main Authors: S. Yu. Klepikova, O. P. Kolesnikova, A. Ye. Prossenko, N. V. Kandalintceva
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
water-soluble antioxidants
immunomodulators
Online Access:https://www.mimmun.ru/mimmun/article/view/170
Description
Summary:Abstract. A study of immunotropic properties of ω-(3,5-dimethyl-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-11-7), and ω-(3,5-di-tret-butil-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-17-7) was carried out, employing an in vitro model of spontaneous and mitogen- stimulated proliferation of cultured spleen cells. It is revealed, that the F-11-7 and F-17-7 compounds are able to suppress proliferation of intact splenocytes in a dose-dependent manner. (Med. Immunol., 2008, vol. 10, n 2-3, pp 269-272).
ISSN:1563-0625
2313-741X

Similar Items