IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy

Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized systemic condition characterized by particular clinical, serologic, and pathologic features that are consistent across a wide range of organ systems. Herein, we present a rare case of IgG4-RD presenting as multiple inflammator...

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Main Authors: Jerasit Surintrspanont, Anapat Sanpawat, Kewalee Sasiwimonphan, Piyada Sitthideatphaiboon
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Urology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442019301470
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spelling doaj-72d0eecbca13483fba09b17839b753e62020-11-25T02:44:55ZengElsevierUrology Case Reports2214-44202019-09-0126IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancyJerasit Surintrspanont0Anapat Sanpawat1Kewalee Sasiwimonphan2Piyada Sitthideatphaiboon3Department of Pathology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, ThailandDepartment of Pathology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, ThailandDivision of Diagnostic Radiology, Department of Radiology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, ThailandDivision of Medical Oncology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, 1873 Henry Do-Nant Rd, Pathumwan, Bangkok, 10330, Thailand; Corresponding author.Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized systemic condition characterized by particular clinical, serologic, and pathologic features that are consistent across a wide range of organ systems. Herein, we present a rare case of IgG4-RD presenting as multiple inflammatory pseudotumors involving the kidney and other organs involvement mimicking urothelial cell carcinoma with liver, lymph node and lung metastasis. The final diagnosis was made based on characteristic histopathological finding and analysis of IgG4 immunostaining that can distinguish from other conditions. Greater awareness of this disease is needed to ensure diagnoses, which can prevent unnecessary surgical intervention. Keywords: IgG4-related disease, Inflammatory pseudotumor, Urothelial carcinomahttp://www.sciencedirect.com/science/article/pii/S2214442019301470
collection DOAJ
language English
format Article
sources DOAJ
author Jerasit Surintrspanont
Anapat Sanpawat
Kewalee Sasiwimonphan
Piyada Sitthideatphaiboon
spellingShingle Jerasit Surintrspanont
Anapat Sanpawat
Kewalee Sasiwimonphan
Piyada Sitthideatphaiboon
IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
Urology Case Reports
author_facet Jerasit Surintrspanont
Anapat Sanpawat
Kewalee Sasiwimonphan
Piyada Sitthideatphaiboon
author_sort Jerasit Surintrspanont
title IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
title_short IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
title_full IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
title_fullStr IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
title_full_unstemmed IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
title_sort igg4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy
publisher Elsevier
series Urology Case Reports
issn 2214-4420
publishDate 2019-09-01
description Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized systemic condition characterized by particular clinical, serologic, and pathologic features that are consistent across a wide range of organ systems. Herein, we present a rare case of IgG4-RD presenting as multiple inflammatory pseudotumors involving the kidney and other organs involvement mimicking urothelial cell carcinoma with liver, lymph node and lung metastasis. The final diagnosis was made based on characteristic histopathological finding and analysis of IgG4 immunostaining that can distinguish from other conditions. Greater awareness of this disease is needed to ensure diagnoses, which can prevent unnecessary surgical intervention. Keywords: IgG4-related disease, Inflammatory pseudotumor, Urothelial carcinoma
url http://www.sciencedirect.com/science/article/pii/S2214442019301470
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