Regulated protein expression for in vivo gene therapy for neurological disorders: Progress, strategies, and issues
The field of in vivo gene therapy has matured to the point where there are numerous clinical trials underway including late-stage clinical trials. Several viral vectors are especially efficient and support lifetime protein expression in the brain and a number of clinical trials are underway for vari...
Main Authors: | Fredric P. Manfredsson, David C. Bloom, Ronald J. Mandel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996112000721 |
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