Effects of bifidobacterium-containing enteral nutrition intervention on the nutritional status and intestinal flora disturbance in patients with the severe cerebral infarction

• Main Authors: Yi Zhang, Jun Wang, Hai-Long Zhu, Yi Liang, Juan Wu
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2017-06-01
• Series: Journal of Hainan Medical University
• Subjects: Severe cerebral infarction Enteral nutrition Bifidobacterium Nutritional status Intestinal flora disturbance
• Online Access: http://www.hnykdxxb.com/PDF/201712/38.pdf

Objective: To study the effects of bifidobacterium-containing enteral nutrition intervention on the nutritional status and intestinal flora disturbance in patients with the severe cerebral infarction. Methods: 88 patients with severe cerebral infarction who were treated in Deyang Second People’s Hospital between March 2014 and October 2016 were collected and divided into control group and observation group according to the random number table, control group received routine enteral nutrition intervention, and the observation group received bifidobacterium-containing enteral nutrition intervention. The nutritional status, intestinal mucosa function and intestinal flora distribution before and after nutritional intervention were compared between the two groups of patients. Results: Before intervention, differences in the nutritional status, intestinal mucosa function and intestinal flora distribution were not statistically significant between two groups of patients. After intervention, peripheral blood levels of nutritional status indexes Hb, TP, ALB, PA and TF in observation group were higher than those in control group; serum levels of intestinal mucosal barrier function indexes DAO and D-lactate were lower than those in control group; the number of bifidobacterium and lactobacillus in feces were larger than those in control group while the number of enterobacteria and enterococcus were smaller than those in control group. Conclusion: Bifidobacterium-containing enteral nutrition intervention can enhance the nutritional status, optimize the intestinal mucosa function and reduce the intestinal flora disturbance in patients with severe cerebral infarction.