Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer

Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer

Abstract Background Almost all of the extracellular matrix (ECM) components can be degraded by the endoproteinases matrix metalloproteinases (MMPs). Important regulators of MMPs, and thereby of the extracellular environment, are tissue inhibitors of metalloproteinases (TIMPs), and especially TIMP-1....

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Bibliographic Details
Main Authors: Camilla Böckelman, Ines Beilmann-Lehtonen, Tuomas Kaprio, Selja Koskensalo, Taina Tervahartiala, Harri Mustonen, Ulf-Håkan Stenman, Timo Sorsa, Caj Haglund
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Colon cancer
MMP-8
MMP-9
TIMP-1
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12885-018-4589-x

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