Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population

Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population

Genetic factors and gene polymorphisms leading to the onset of autoimmune response in autoimmune hepatitis (AIH) are still not full elucidated. Since the CTLA-4 molecule is a key modulator of the lymphocytes responses we hypothezied that deficiencies or mutations in the gene encoding CTLA4 protein m...

Full description

Bibliographic Details
Main Authors: Marwa Chaouali, Agostinho Carvalho, Aymen Tezeghdenti, Mouna Ben Azaiez, Cristina Cunha, Ezzeddine Ghazouani, Radhia Kochkar
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304217301034

Similar Items

Similar Items