1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation

1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation

1-Nitropyrene (1-NP), one of the most abundant nitropolycyclic aromatic hydrocarbons (nitro-PAHs), is generated from the incomplete combustion of carbonaceous organic compounds. 1-NP is a specific marker of diesel exhaust and is an environmental pollutant and a probable carcinogen. Macrophages parti...

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Bibliographic Details
Main Authors:	Chun-Hung Su, Yung-Chuan Ho, Min-Wei Lee, Ching-Chi Tseng, Shiuan-Shinn Lee, Ming Kun Hsieh, Hsin-Hung Chen, Chien-Ying Lee, Sheng-Wen Wu, Yu-Hsiang Kuan
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2021/9314342

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