VEGF‐B: a more balanced approach toward cardiac neovascularization?

There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF‐B in the rat heart leads to expansion of the coronary arterial tree and an increase...

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Main Authors: Christian Kupatt, Rabea Hinkel
Format: Article
Language:English
Published: Wiley 2014-03-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.1002/emmm.201303730
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spelling doaj-72af0b26c7af43529af0339380e7a08d2021-08-02T19:14:09ZengWileyEMBO Molecular Medicine1757-46761757-46842014-03-016329729810.1002/emmm.201303730VEGF‐B: a more balanced approach toward cardiac neovascularization?Christian Kupatt0Rabea Hinkel1Medizinische Klinik I Klinikum Großhadern Munich GermanyMedizinische Klinik I Klinikum Großhadern Munich GermanyThere is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF‐B in the rat heart leads to expansion of the coronary arterial tree and an increase in functional coronary reserve, accompanied by a shift in myocardial metabolism from fatty acid to glucose utilization.https://doi.org/10.1002/emmm.201303730
collection DOAJ
language English
format Article
sources DOAJ
author Christian Kupatt
Rabea Hinkel
spellingShingle Christian Kupatt
Rabea Hinkel
VEGF‐B: a more balanced approach toward cardiac neovascularization?
EMBO Molecular Medicine
author_facet Christian Kupatt
Rabea Hinkel
author_sort Christian Kupatt
title VEGF‐B: a more balanced approach toward cardiac neovascularization?
title_short VEGF‐B: a more balanced approach toward cardiac neovascularization?
title_full VEGF‐B: a more balanced approach toward cardiac neovascularization?
title_fullStr VEGF‐B: a more balanced approach toward cardiac neovascularization?
title_full_unstemmed VEGF‐B: a more balanced approach toward cardiac neovascularization?
title_sort vegf‐b: a more balanced approach toward cardiac neovascularization?
publisher Wiley
series EMBO Molecular Medicine
issn 1757-4676
1757-4684
publishDate 2014-03-01
description There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF‐B in the rat heart leads to expansion of the coronary arterial tree and an increase in functional coronary reserve, accompanied by a shift in myocardial metabolism from fatty acid to glucose utilization.
url https://doi.org/10.1002/emmm.201303730
work_keys_str_mv AT christiankupatt vegfbamorebalancedapproachtowardcardiacneovascularization
AT rabeahinkel vegfbamorebalancedapproachtowardcardiacneovascularization
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