VEGF‐B: a more balanced approach toward cardiac neovascularization?

There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF‐B in the rat heart leads to expansion of the coronary arterial tree and an increase...

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Bibliographic Details
Main Authors: Christian Kupatt, Rabea Hinkel
Format: Article
Language:English
Published: Wiley 2014-03-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.1002/emmm.201303730
Description
Summary:There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF‐B in the rat heart leads to expansion of the coronary arterial tree and an increase in functional coronary reserve, accompanied by a shift in myocardial metabolism from fatty acid to glucose utilization.
ISSN:1757-4676
1757-4684