Nitro-Heterocyclic compounds induce apoptosis-like effects in Leishmania (L). amazonensis promastigotes

Abstract Background: Three drugs - pentavalent antimonials, amphotericin B and pentamidine - are currently used for leishmaniasis treatment. They are administered for long periods, only parenterally, and have high cardiac, renal and hepatic toxicities. Therefore, the investigation of new compounds...

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Bibliographic Details
Main Authors: Daiane Barros Dias Mendonça, Renata Ellen Costa Silva, Fanny Palace-Berl, Cleusa FH Takakura, Sandra Regina C Soares, Lucia Maria Almeida Braz, Leoberto Costa Tavares, Jose Angelo Lauletta Lindoso
Format: Article
Language:English
Published: SciELO 2019-03-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100303&lng=en&tlng=en