Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review

Objective. Cesarean scar pregnancy (CSP) is a rare condition that occurs when the pregnancy implants in a cesarean scar. An early diagnosis and a proper management are fundamental to prevent maternal complications. We review and discuss the different treatment employed in our unit to reduce morbidit...

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Main Authors: P. Giampaolino, N. De Rosa, I. Morra, A. Bertrando, A. Di Spiezio Sardo, B. Zizolfi, C. Ferrara, L. Della Corte, G. Bifulco
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/6486407
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spelling doaj-72a10128b5784e49b97be8fd96465d432020-11-24T23:31:39ZengHindawi LimitedBioMed Research International2314-61332314-61412018-01-01201810.1155/2018/64864076486407Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective ReviewP. Giampaolino0N. De Rosa1I. Morra2A. Bertrando3A. Di Spiezio Sardo4B. Zizolfi5C. Ferrara6L. Della Corte7G. Bifulco8Department of Public Health, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyObjective. Cesarean scar pregnancy (CSP) is a rare condition that occurs when the pregnancy implants in a cesarean scar. An early diagnosis and a proper management are fundamental to prevent maternal complications. We review and discuss the different treatment employed in our unit to reduce morbidity, preserve fertility, and predict possible complications. Methods. The reported treatment has been expectant management, operative hysteroscopy approach, and intramuscular injection of 50 mg methotrexate (MTX), followed by cervical dilation and manual vacuum aspiration (D&S) with a Karman cannula under ultrasound guidance, uterine artery embolization (UAE), and manual vacuum aspiration under ultrasound guidance and uterine artery embolization before surgical laparotomic resection. Results. Complications were more frequent in women with a history of three or more cesarean section deliveries and with a myometrial thickness thinner than 2 mm. MTX and D&S treatment appear to be most effective and safe at the early age of pregnancy, while UAE and D&S are related to the highest risk of complication in any age of pregnancy. Conclusion. An appropriate preoperative diagnostic evaluation, the identification of cases at higher risk, and those eligible for a conservative treatment are fundamental to reduce complications.http://dx.doi.org/10.1155/2018/6486407
collection DOAJ
language English
format Article
sources DOAJ
author P. Giampaolino
N. De Rosa
I. Morra
A. Bertrando
A. Di Spiezio Sardo
B. Zizolfi
C. Ferrara
L. Della Corte
G. Bifulco
spellingShingle P. Giampaolino
N. De Rosa
I. Morra
A. Bertrando
A. Di Spiezio Sardo
B. Zizolfi
C. Ferrara
L. Della Corte
G. Bifulco
Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review
BioMed Research International
author_facet P. Giampaolino
N. De Rosa
I. Morra
A. Bertrando
A. Di Spiezio Sardo
B. Zizolfi
C. Ferrara
L. Della Corte
G. Bifulco
author_sort P. Giampaolino
title Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review
title_short Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review
title_full Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review
title_fullStr Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review
title_full_unstemmed Management of Cesarean Scar Pregnancy: A Single-Institution Retrospective Review
title_sort management of cesarean scar pregnancy: a single-institution retrospective review
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2018-01-01
description Objective. Cesarean scar pregnancy (CSP) is a rare condition that occurs when the pregnancy implants in a cesarean scar. An early diagnosis and a proper management are fundamental to prevent maternal complications. We review and discuss the different treatment employed in our unit to reduce morbidity, preserve fertility, and predict possible complications. Methods. The reported treatment has been expectant management, operative hysteroscopy approach, and intramuscular injection of 50 mg methotrexate (MTX), followed by cervical dilation and manual vacuum aspiration (D&S) with a Karman cannula under ultrasound guidance, uterine artery embolization (UAE), and manual vacuum aspiration under ultrasound guidance and uterine artery embolization before surgical laparotomic resection. Results. Complications were more frequent in women with a history of three or more cesarean section deliveries and with a myometrial thickness thinner than 2 mm. MTX and D&S treatment appear to be most effective and safe at the early age of pregnancy, while UAE and D&S are related to the highest risk of complication in any age of pregnancy. Conclusion. An appropriate preoperative diagnostic evaluation, the identification of cases at higher risk, and those eligible for a conservative treatment are fundamental to reduce complications.
url http://dx.doi.org/10.1155/2018/6486407
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