A Double-Switch Cell Fusion-Inducible Transgene Expression System for Neural Stem Cell-Based Antiglioma Gene Therapy

A Double-Switch Cell Fusion-Inducible Transgene Expression System for Neural Stem Cell-Based Antiglioma Gene Therapy

Recent progress in neural stem cell- (NSC-) based tumor-targeted gene therapy showed that NSC vectors expressing an artificially engineered viral fusogenic protein, VSV-G H162R, could cause tumor cell death specifically under acidic tumor microenvironment by syncytia formation; however, the killing...

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Bibliographic Details
Main Authors:	Yumei Luo, Detu Zhu, Dang Hoang Lam, Juan Huang, Yi Tang, Xitu Luo, Shu Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2015/649080

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