Connection between oligomeric state and gating characteristics of mechanosensitive ion channels.

The mechanosensitive channel of large conductance (MscL) is capable of transducing mechanical stimuli such as membrane tension into an electrochemical response. MscL provides a widely-studied model system for mechanotransduction and, more generally, for how bilayer mechanical properties regulate pro...

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Bibliographic Details
Main Authors: Christoph A Haselwandter, Rob Phillips
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3656111?pdf=render