Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer

Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer

Breast cancer (BC) is a global public health burden, constituting the highest cancer incidence in women worldwide. Connexin43 (Cx43) is a member of a family of transmembrane proteins responsible in part for intercellular communication between adjacent breast epithelial cells, via gap junctions. Cx43...

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Bibliographic Details
Main Authors: Nataly Naser Al Deen, Mounir AbouHaidar, Rabih Talhouk
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Medicine
Subjects:
gap junctions
connexins
breast cancer
microRNAs
circularRNAs
tumor-suppressors
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00192/full

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