Novel deprotection method of Fmoc group using nano-K2CO3

Novel deprotection method of Fmoc group using nano-K2CO3

Fmoc is usually used as an amino-protecting group. The traditional removal method is realized by using a secondary amine. However, this method has some shortcomings including high cost, difficult recycle of excess secondary amine and environmental pollution. The paper reports a novel heterogeneous d...

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Bibliographic Details
Main Authors: Shiming FAN, Runjiao LIU, Yuan ZHAO, Shuo LI, Xingchi LI, Peng WANG, Shouxin LIU
Format: Article
Language:zho
Published: Hebei University of Science and Technology 2018-06-01
Series:Journal of Hebei University of Science and Technology
Subjects:
organic synthesis chemistry
nano-K2CO3
Fmoc
deprotection
amino acid
peptide
Online Access:http://xuebao.hebust.edu.cn/hbkjdx/ch/reader/create_pdf.aspx?file_no=b201803008&flag=1&journal_

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http://xuebao.hebust.edu.cn/hbkjdx/ch/reader/create_pdf.aspx?file_no=b201803008&flag=1&journal_

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