Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection
The SARS-CoV-2 pandemic is continuing to impact the global population, and knowledge of the immune response to COVID-19 is still developing. This study assesses the interplay of different parts of the immune system during COVID-19 disease.
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American Society for Microbiology
2021-02-01
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| Series: | mSphere |
| Online Access: | https://journals.asm.org/doi/10.1128/mSphere.01324-20 |
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doaj-7291606a068442be9db403b0d8e1d2b62021-09-21T20:22:52ZengAmerican Society for MicrobiologymSphere2379-50422021-02-016110.1128/mSphere.01324-20Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 InfectionAlexander M. Horspool0https://orcid.org/0000-0003-4115-0331Theodore Kieffer1Brynnan P. Russ2Megan A. DeJong3M. Allison Wolf4https://orcid.org/0000-0002-9540-9647Jacqueline M. Karakiozis5Brice J. Hickey6Paolo Fagone7Danyel H. Tacker8Justin R. Bevere9Ivan Martinez10Mariette Barbier11https://orcid.org/0000-0002-3250-3636Peter L. Perrotta12F. Heath Damron13https://orcid.org/0000-0002-3140-402XDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USADepartment of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USADepartment of Biochemistry, West Virginia University, Morgantown, West Virginia, USADepartment of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USADepartment of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USADepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA The SARS-CoV-2 pandemic is continuing to impact the global population, and knowledge of the immune response to COVID-19 is still developing. This study assesses the interplay of different parts of the immune system during COVID-19 disease.https://journals.asm.org/doi/10.1128/mSphere.01324-20 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Alexander M. Horspool Theodore Kieffer Brynnan P. Russ Megan A. DeJong M. Allison Wolf Jacqueline M. Karakiozis Brice J. Hickey Paolo Fagone Danyel H. Tacker Justin R. Bevere Ivan Martinez Mariette Barbier Peter L. Perrotta F. Heath Damron |
| spellingShingle |
Alexander M. Horspool Theodore Kieffer Brynnan P. Russ Megan A. DeJong M. Allison Wolf Jacqueline M. Karakiozis Brice J. Hickey Paolo Fagone Danyel H. Tacker Justin R. Bevere Ivan Martinez Mariette Barbier Peter L. Perrotta F. Heath Damron Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection mSphere |
| author_facet |
Alexander M. Horspool Theodore Kieffer Brynnan P. Russ Megan A. DeJong M. Allison Wolf Jacqueline M. Karakiozis Brice J. Hickey Paolo Fagone Danyel H. Tacker Justin R. Bevere Ivan Martinez Mariette Barbier Peter L. Perrotta F. Heath Damron |
| author_sort |
Alexander M. Horspool |
| title |
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection |
| title_short |
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection |
| title_full |
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection |
| title_fullStr |
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection |
| title_full_unstemmed |
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection |
| title_sort |
interplay of antibody and cytokine production reveals cxcl13 as a potential novel biomarker of lethal sars-cov-2 infection |
| publisher |
American Society for Microbiology |
| series |
mSphere |
| issn |
2379-5042 |
| publishDate |
2021-02-01 |
| description |
The SARS-CoV-2 pandemic is continuing to impact the global population, and knowledge of the immune response to COVID-19 is still developing. This study assesses the interplay of different parts of the immune system during COVID-19 disease. |
| url |
https://journals.asm.org/doi/10.1128/mSphere.01324-20 |
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