Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication

Currently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capab...

Full description

Bibliographic Details
Main Authors: Mykola Borzenkov, Giuseppe Chirico, Piersandro Pallavicini, Paola Sperandeo, Alessandra Polissi, Giacomo Dacarro, Lavinia Doveri, Maddalena Collini, Laura Sironi, Margaux Bouzin, Laura D’Alfonso
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/10/4/786
id doaj-727b8e4d7b314d3a8d063115c185f72a
record_format Article
spelling doaj-727b8e4d7b314d3a8d063115c185f72a2020-11-25T02:21:36ZengMDPI AGNanomaterials2079-49912020-04-011078678610.3390/nano10040786Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria EradicationMykola Borzenkov0Giuseppe Chirico1Piersandro Pallavicini2Paola Sperandeo3Alessandra Polissi4Giacomo Dacarro5Lavinia Doveri6Maddalena Collini7Laura Sironi8Margaux Bouzin9Laura D’Alfonso10Department of Medicine and Surgery, Nanomedicine Center, University of Milano-Bicocca, Via Raoul Follereau 3, 20854 Vedano al Lambro (MB), ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, ItalyDepartment of Pharmacological and Biomolecular Sciences, University of Milano, via Balzaretti 9, 20133 Milan, ItalyDepartment of Pharmacological and Biomolecular Sciences, University of Milano, via Balzaretti 9, 20133 Milan, ItalyDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, ItalyDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyCurrently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capable of eradicating bacteria. In this work, we fabricated antibacterial films obtained by spraying on glass slides aqueous solutions of polymers, containing highly photo-thermally active gold nanostars (GNS) or Prussian Blue (PB) nanoparticles. Under NIR light irradiation with low intensities (0.35 W/cm<sup>2</sup>) these films demonstrated a pronounced photo-thermal effect: Δ<i>T<sub>max</sub></i> up to 26.4 °C for the GNS-containing films and Δ<i>T<sub>max</sub></i> up to 45.8 °C for the PB-containing films. In the latter case, such a local temperature increase demonstrated a remarkable effect on a Gram-negative strain (<i>P. aeruginosa</i>) killing (84% of dead bacteria), and a promising effect on a Gram-positive strain (<i>S. aureus</i>) eradication (69% of dead bacteria). The fabricated films are promising prototypes for further development of lightweight surfaces with efficient antibacterial action that can be remotely activated on demand.https://www.mdpi.com/2079-4991/10/4/786nanoparticlesphoto-thermal effectnanocompositesbacteria eradication
collection DOAJ
language English
format Article
sources DOAJ
author Mykola Borzenkov
Giuseppe Chirico
Piersandro Pallavicini
Paola Sperandeo
Alessandra Polissi
Giacomo Dacarro
Lavinia Doveri
Maddalena Collini
Laura Sironi
Margaux Bouzin
Laura D’Alfonso
spellingShingle Mykola Borzenkov
Giuseppe Chirico
Piersandro Pallavicini
Paola Sperandeo
Alessandra Polissi
Giacomo Dacarro
Lavinia Doveri
Maddalena Collini
Laura Sironi
Margaux Bouzin
Laura D’Alfonso
Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
Nanomaterials
nanoparticles
photo-thermal effect
nanocomposites
bacteria eradication
author_facet Mykola Borzenkov
Giuseppe Chirico
Piersandro Pallavicini
Paola Sperandeo
Alessandra Polissi
Giacomo Dacarro
Lavinia Doveri
Maddalena Collini
Laura Sironi
Margaux Bouzin
Laura D’Alfonso
author_sort Mykola Borzenkov
title Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
title_short Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
title_full Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
title_fullStr Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
title_full_unstemmed Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
title_sort nanocomposite sprayed films with photo-thermal properties for remote bacteria eradication
publisher MDPI AG
series Nanomaterials
issn 2079-4991
publishDate 2020-04-01
description Currently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capable of eradicating bacteria. In this work, we fabricated antibacterial films obtained by spraying on glass slides aqueous solutions of polymers, containing highly photo-thermally active gold nanostars (GNS) or Prussian Blue (PB) nanoparticles. Under NIR light irradiation with low intensities (0.35 W/cm<sup>2</sup>) these films demonstrated a pronounced photo-thermal effect: Δ<i>T<sub>max</sub></i> up to 26.4 °C for the GNS-containing films and Δ<i>T<sub>max</sub></i> up to 45.8 °C for the PB-containing films. In the latter case, such a local temperature increase demonstrated a remarkable effect on a Gram-negative strain (<i>P. aeruginosa</i>) killing (84% of dead bacteria), and a promising effect on a Gram-positive strain (<i>S. aureus</i>) eradication (69% of dead bacteria). The fabricated films are promising prototypes for further development of lightweight surfaces with efficient antibacterial action that can be remotely activated on demand.
topic nanoparticles
photo-thermal effect
nanocomposites
bacteria eradication
url https://www.mdpi.com/2079-4991/10/4/786
work_keys_str_mv AT mykolaborzenkov nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT giuseppechirico nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT piersandropallavicini nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT paolasperandeo nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT alessandrapolissi nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT giacomodacarro nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT laviniadoveri nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT maddalenacollini nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT laurasironi nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT margauxbouzin nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
AT lauradalfonso nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication
_version_ 1724865310105796608