Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication
Currently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capab...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
|
Series: | Nanomaterials |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-4991/10/4/786 |
id |
doaj-727b8e4d7b314d3a8d063115c185f72a |
---|---|
record_format |
Article |
spelling |
doaj-727b8e4d7b314d3a8d063115c185f72a2020-11-25T02:21:36ZengMDPI AGNanomaterials2079-49912020-04-011078678610.3390/nano10040786Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria EradicationMykola Borzenkov0Giuseppe Chirico1Piersandro Pallavicini2Paola Sperandeo3Alessandra Polissi4Giacomo Dacarro5Lavinia Doveri6Maddalena Collini7Laura Sironi8Margaux Bouzin9Laura D’Alfonso10Department of Medicine and Surgery, Nanomedicine Center, University of Milano-Bicocca, Via Raoul Follereau 3, 20854 Vedano al Lambro (MB), ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, ItalyDepartment of Pharmacological and Biomolecular Sciences, University of Milano, via Balzaretti 9, 20133 Milan, ItalyDepartment of Pharmacological and Biomolecular Sciences, University of Milano, via Balzaretti 9, 20133 Milan, ItalyDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, ItalyDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyDepartment of Physics, University of Milano-Bicocca, Piazza della Scienza 3, 20126 Milan, ItalyCurrently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capable of eradicating bacteria. In this work, we fabricated antibacterial films obtained by spraying on glass slides aqueous solutions of polymers, containing highly photo-thermally active gold nanostars (GNS) or Prussian Blue (PB) nanoparticles. Under NIR light irradiation with low intensities (0.35 W/cm<sup>2</sup>) these films demonstrated a pronounced photo-thermal effect: Δ<i>T<sub>max</sub></i> up to 26.4 °C for the GNS-containing films and Δ<i>T<sub>max</sub></i> up to 45.8 °C for the PB-containing films. In the latter case, such a local temperature increase demonstrated a remarkable effect on a Gram-negative strain (<i>P. aeruginosa</i>) killing (84% of dead bacteria), and a promising effect on a Gram-positive strain (<i>S. aureus</i>) eradication (69% of dead bacteria). The fabricated films are promising prototypes for further development of lightweight surfaces with efficient antibacterial action that can be remotely activated on demand.https://www.mdpi.com/2079-4991/10/4/786nanoparticlesphoto-thermal effectnanocompositesbacteria eradication |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mykola Borzenkov Giuseppe Chirico Piersandro Pallavicini Paola Sperandeo Alessandra Polissi Giacomo Dacarro Lavinia Doveri Maddalena Collini Laura Sironi Margaux Bouzin Laura D’Alfonso |
spellingShingle |
Mykola Borzenkov Giuseppe Chirico Piersandro Pallavicini Paola Sperandeo Alessandra Polissi Giacomo Dacarro Lavinia Doveri Maddalena Collini Laura Sironi Margaux Bouzin Laura D’Alfonso Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication Nanomaterials nanoparticles photo-thermal effect nanocomposites bacteria eradication |
author_facet |
Mykola Borzenkov Giuseppe Chirico Piersandro Pallavicini Paola Sperandeo Alessandra Polissi Giacomo Dacarro Lavinia Doveri Maddalena Collini Laura Sironi Margaux Bouzin Laura D’Alfonso |
author_sort |
Mykola Borzenkov |
title |
Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication |
title_short |
Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication |
title_full |
Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication |
title_fullStr |
Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication |
title_full_unstemmed |
Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication |
title_sort |
nanocomposite sprayed films with photo-thermal properties for remote bacteria eradication |
publisher |
MDPI AG |
series |
Nanomaterials |
issn |
2079-4991 |
publishDate |
2020-04-01 |
description |
Currently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capable of eradicating bacteria. In this work, we fabricated antibacterial films obtained by spraying on glass slides aqueous solutions of polymers, containing highly photo-thermally active gold nanostars (GNS) or Prussian Blue (PB) nanoparticles. Under NIR light irradiation with low intensities (0.35 W/cm<sup>2</sup>) these films demonstrated a pronounced photo-thermal effect: Δ<i>T<sub>max</sub></i> up to 26.4 °C for the GNS-containing films and Δ<i>T<sub>max</sub></i> up to 45.8 °C for the PB-containing films. In the latter case, such a local temperature increase demonstrated a remarkable effect on a Gram-negative strain (<i>P. aeruginosa</i>) killing (84% of dead bacteria), and a promising effect on a Gram-positive strain (<i>S. aureus</i>) eradication (69% of dead bacteria). The fabricated films are promising prototypes for further development of lightweight surfaces with efficient antibacterial action that can be remotely activated on demand. |
topic |
nanoparticles photo-thermal effect nanocomposites bacteria eradication |
url |
https://www.mdpi.com/2079-4991/10/4/786 |
work_keys_str_mv |
AT mykolaborzenkov nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT giuseppechirico nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT piersandropallavicini nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT paolasperandeo nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT alessandrapolissi nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT giacomodacarro nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT laviniadoveri nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT maddalenacollini nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT laurasironi nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT margauxbouzin nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication AT lauradalfonso nanocompositesprayedfilmswithphotothermalpropertiesforremotebacteriaeradication |
_version_ |
1724865310105796608 |