VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis

VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis

Cancer and neurodegeneration are different classes of diseases that share the involvement of mitochondria in their pathogenesis. Whereas the high glycolytic rate (the so-called Warburg metabolism) and the suppression of apoptosis are key elements for the establishment and maintenance of cancer cells...

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Bibliographic Details
Main Authors: Andrea Magrì, Simona Reina, Vito De Pinto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Chemistry
Subjects:
mitochondria
apoptosis
VDAC
peptides
oligos
microRNAs
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2018.00108/full

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