Cdx2 polymorphism affects the activities of vitamin D receptor in human breast cancer cell lines and human breast carcinomas.

Vitamin D plays a role in cancer development and acts through the vitamin D receptor (VDR). It regulates the action of hormone responsive genes and is involved in cell cycle regulation, differentiation and apoptosis. VDR is a critical component of the vitamin D pathway and different common single nu...

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Bibliographic Details
Main Authors: Claudio Pulito, Irene Terrenato, Anna Di Benedetto, Etleva Korita, Frauke Goeman, Andrea Sacconi, Francesca Biagioni, Giovanni Blandino, Sabrina Strano, Paola Muti, Marcella Mottolese, Elisabetta Falvo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388514?pdf=render

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