Sphingomyelin liposome bearing whole Leishmania lysate antigens induce strong Th2 immune response in BALB/c mice

Sphingomyelin liposome bearing whole Leishmania lysate antigens induce strong Th2 immune response in BALB/c mice

Objective(s): Whole Leishmania lysate antigens (WLL) has been shown to be effective to tackle leishmaniasis in murine models. Although liposomes can be considered as promising vaccines, the activity of phospholipase-A (PLA) in WLL, breeds difficulties to preparing stable liposomal WLL. One strategy...

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Bibliographic Details
Main Authors: Nazanin Biari, Seyedeh Hoda Alavizadeh, Omid Chavoshian, Azam Abbasi, Zahra Saberi, Seyed Amir Jalali, Ali Khamesipoure, Mahmoud Reza Jaafari, Ali Badiee
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
balb c mouse humoral immunity leishmaniasis vaccines liposomes phospholipase
a
Online Access:https://ijbms.mums.ac.ir/article_17192_4305b47f7d9de57c09790d338a5c218d.pdf

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https://ijbms.mums.ac.ir/article_17192_4305b47f7d9de57c09790d338a5c218d.pdf

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