Uremic Toxins in Organ Crosstalk

Many putative uremic toxins—like indoxyl sulfate, p-cresol sulfate, kynurenic acid, uric acid, and CMPF—are organic anions. Both inter-organ and inter-organismal communication are involved. For example, the gut microbiome is the main source of indole, which, after modification by liver drug metaboli...

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Bibliographic Details
Main Authors: Jerome Lowenstein, Sanjay K. Nigam
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.592602/full