The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases

Fuzheng Huayu formula (FZHY) is a traditional Chinese medicine formula composed of Radix Salvia Miltiorrhizae, Cordyceps, Semen Persicae, Gynostemma Pentaphyllammak, Pollen Pini, Fructus Schisandrae Chinensis that is used to treat chronic liver diseases in China. We here describe the pharmacological...

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Main Authors: Jiamei Chen, Yonghong Hu, Long Chen, Wei Liu, Yongping Mu, Ping Liu
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219300563
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spelling doaj-725c4423dca349f38a12db9b9f4836ea2021-05-21T04:17:11ZengElsevierBiomedicine & Pharmacotherapy0753-33222019-06-01114The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseasesJiamei Chen0Yonghong Hu1Long Chen2Wei Liu3Yongping Mu4Ping Liu5Institute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, ChinaInstitute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, China; E-Institute of Shanghai Municipal Education Commission Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Corresponding author at: Institute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.Fuzheng Huayu formula (FZHY) is a traditional Chinese medicine formula composed of Radix Salvia Miltiorrhizae, Cordyceps, Semen Persicae, Gynostemma Pentaphyllammak, Pollen Pini, Fructus Schisandrae Chinensis that is used to treat chronic liver diseases in China. We here describe the pharmacological actions of FZHY in this review. We also describe and provide updates on recent advances in the medical applications and the basic research of mechanisms of FZHY formula. FZHY has been shown to have no serious adverse reactions and exerts antifibrotic effects through targeting more than one molecule.http://www.sciencedirect.com/science/article/pii/S0753332219300563Fuzheng HuayuChronic liver diseaseClinical applicationAntifibrotic effectMechanism
collection DOAJ
language English
format Article
sources DOAJ
author Jiamei Chen
Yonghong Hu
Long Chen
Wei Liu
Yongping Mu
Ping Liu
spellingShingle Jiamei Chen
Yonghong Hu
Long Chen
Wei Liu
Yongping Mu
Ping Liu
The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases
Biomedicine & Pharmacotherapy
Fuzheng Huayu
Chronic liver disease
Clinical application
Antifibrotic effect
Mechanism
author_facet Jiamei Chen
Yonghong Hu
Long Chen
Wei Liu
Yongping Mu
Ping Liu
author_sort Jiamei Chen
title The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases
title_short The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases
title_full The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases
title_fullStr The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases
title_full_unstemmed The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases
title_sort effect and mechanisms of fuzheng huayu formula against chronic liver diseases
publisher Elsevier
series Biomedicine & Pharmacotherapy
issn 0753-3322
publishDate 2019-06-01
description Fuzheng Huayu formula (FZHY) is a traditional Chinese medicine formula composed of Radix Salvia Miltiorrhizae, Cordyceps, Semen Persicae, Gynostemma Pentaphyllammak, Pollen Pini, Fructus Schisandrae Chinensis that is used to treat chronic liver diseases in China. We here describe the pharmacological actions of FZHY in this review. We also describe and provide updates on recent advances in the medical applications and the basic research of mechanisms of FZHY formula. FZHY has been shown to have no serious adverse reactions and exerts antifibrotic effects through targeting more than one molecule.
topic Fuzheng Huayu
Chronic liver disease
Clinical application
Antifibrotic effect
Mechanism
url http://www.sciencedirect.com/science/article/pii/S0753332219300563
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