Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery

Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery

Opportunistic fungi are a major cause of morbidity and mortality world-wide, particularly in immunocompromised individuals. Developing new treatments to combat invasive fungal disease is challenging given that fungal and mammalian host cells are eukaryotic, with similar organization and physiology....

Full description

Bibliographic Details
Main Authors: Cecilia Li, Sophie Lev, Adolfo Saiardi, Desmarini Desmarini, Tania C. Sorrell, Julianne T. Djordjevic
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Journal of Fungi
Subjects:
antifungal compounds
Cryptococcus neoformans
inositol polyphosphate kinases
inositol pyrophosphates
PP-IP5
fungal virulence
cryptococcal meningitis
drug discovery
Online Access:http://www.mdpi.com/2309-608X/2/3/24

Internet

http://www.mdpi.com/2309-608X/2/3/24

Similar Items