Peptidoglycan recognition proteins kill bacteria by inducing oxidative, thiol, and metal stress.

Peptidoglycan recognition proteins kill bacteria by inducing oxidative, thiol, and metal stress.

Mammalian Peptidoglycan Recognition Proteins (PGRPs) are a family of evolutionary conserved bactericidal innate immunity proteins, but the mechanism through which they kill bacteria is unclear. We previously proposed that PGRPs are bactericidal due to induction of reactive oxygen species (ROS), a me...

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Bibliographic Details
Main Authors:	Des Raj Kashyap, Annemarie Rompca, Ahmed Gaballa, John D Helmann, Jefferson Chan, Christopher J Chang, Iztok Hozo, Dipika Gupta, Roman Dziarski
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-07-01
Series:	PLoS Pathogens
Online Access:	http://europepmc.org/articles/PMC4102600?pdf=render

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