The Diuretic Effect of Sairei-to Is Mediated by Nitric Oxide Production in Pentobarbital-Anesthetized Rats

Sairei-to (TJ-114), a Japanese traditional medicine, has been used clinically for the treatment of various edematous disorders. The inhibitory effect on edema may be dependent on the diuretic response to TJ-114. This study was conducted to clarify the mechanism of diuresis. Pentobarbital-anesthetize...

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Bibliographic Details
Main Authors: Naoki Fujitsuka, Kazuhiro Goto, Shuichi Takeda, Masaki Aburada
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325241