Genome-wide comparison of Corynebacterium diphtheriae isolates from Australia identifies differences in the Pan-genomes between respiratory and cutaneous strains

Genome-wide comparison of Corynebacterium diphtheriae isolates from Australia identifies differences in the Pan-genomes between respiratory and cutaneous strains

Abstract Background Corynebacterium diphtheriae is the main etiological agent of diphtheria, a global disease causing life-threatening infections, particularly in infants and children. Vaccination with diphtheria toxoid protects against infection with potent toxin producing strains. However a growin...

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Bibliographic Details
Main Authors: Verlaine J. Timms, Trang Nguyen, Taryn Crighton, Marion Yuen, Vitali Sintchenko
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Genomics
Subjects:
Whole genome sequencing
Diphtheria
Vaccine preventable disease
Molecular epidemiology
Pan-genome analysis
Virulence
Online Access:http://link.springer.com/article/10.1186/s12864-018-5147-2

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