Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.

Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.

Infection is a frequent and serious complication following the treatment of hydrocephalus with CSF shunts, with limited therapeutic options because of biofilm formation along the catheter surface. Here we evaluated the possibility that the sarA regulatory locus engenders S. aureus more resistant to...

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Bibliographic Details
Main Authors: Jessica N Snowden, Matt Beaver, Karen Beenken, Mark Smeltzer, Alexander R Horswill, Tammy Kielian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3875531?pdf=render

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