Progress and challenges in TB vaccine development [version 1; referees: 2 approved]

Progress and challenges in TB vaccine development [version 1; referees: 2 approved]

The Bacille Calmette Guerin (BCG) vaccine can provide decades of protection against tuberculosis (TB) disease, and although imperfect, BCG is proof that vaccine mediated protection against TB is a possibility. A new TB vaccine is, therefore, an inevitability; the question is how long will it take us...

Full description

Bibliographic Details
Main Authors:	Gerald Voss, Danilo Casimiro, Olivier Neyrolles, Ann Williams, Stefan H.E. Kaufmann, Helen McShane, Mark Hatherill, Helen A Fletcher
Format:	Article
Language:	English
Published:	F1000 Research Ltd 2018-02-01
Series:	F1000Research
Online Access:	https://f1000research.com/articles/7-199/v1

Similar Items

VALIDATE: Exploiting the synergy between complex intracellular pathogens to expedite vaccine research and development for tuberculosis, leishmaniasis, melioidosis and leprosy [version 1; referees: 2 approved]
by: Helen A. Fletcher, et al.
Published: (2018-04-01)

Social determinants and BCG efficacy: a call for a socio-biological approach to TB prevention [version 1; referees: 2 approved]
by: Jennifer B. Dowd, et al.
Published: (2018-02-01)

Factors influencing the higher incidence of tuberculosis among migrants and ethnic minorities in the UK [version 2; referees: 2 approved]
by: Sally Hayward, et al.
Published: (2018-08-01)

The convergent epidemiology of tuberculosis and human cytomegalovirus infection [version 2; referees: 2 approved]
by: Frank Cobelens, et al.
Published: (2018-04-01)

Matchmaking in Bioinformatics [version 1; referees: 2 approved]
by: Ewy Mathé, et al.
Published: (2018-02-01)

Chikungunya: vaccines and therapeutics [version 1; referees: 2 approved]
by: Kothila Tharmarajah, et al.
Published: (2017-12-01)

The mesh controversy [version 1; referees: 2 approved]
by: Joshua A. Cohn, et al.
Published: (2016-09-01)

Chikungunya: epidemiology [version 1; referees: 2 approved]
by: Lyle R. Petersen, et al.
Published: (2016-01-01)

Human papillomavirus vaccination: the population impact [version 1; referees: 3 approved]
by: Lai-yang Lee, et al.
Published: (2017-06-01)

Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial [version 1; referees: 3 approved]
by: Ray Y. Chen, et al.
Published: (2017-11-01)

Mitochondrial apoptosis and BH3 mimetics [version 1; referees: 3 approved]
by: Haiming Dai, et al.
Published: (2016-12-01)

Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients [version 1; referees: 2 approved, 1 approved with reservations]
by: Benjamin Patterson, et al.
Published: (2017-11-01)

Pneumococcal Conjugate Vaccine impact assessment in Bangladesh [version 1; referees: 1 approved, 2 approved with reservations]
by: Abdullah H. Baqui, et al.
Published: (2018-04-01)

Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients [version 2; referees: 3 approved]
by: Benjamin Patterson, et al.
Published: (2018-06-01)

Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions [version 1; referees: 3 approved]
by: Helen Su
Published: (2017-03-01)

Podocytes [version 1; referees: 2 approved]
by: Jochen Reiser, et al.
Published: (2016-01-01)

Nephrotoxicities [version 1; referees: 2 approved]
by: Stuart L. Goldstein
Published: (2017-01-01)

Tumour Cell Heterogeneity [version 1; referees: 5 approved]
by: Laura Gay, et al.
Published: (2016-02-01)

Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: comparison with boosting with a new TB vaccine, MVA85A.
by: Kathryn T Whelan, et al.
Published: (2009-06-01)

Advances in the management of osteosarcoma [version 1; referees: 2 approved]
by: Stefan S. Bielack, et al.
Published: (2016-11-01)

Recent developments in osteogenesis imperfecta [version 1; referees: 3 approved]
by: Joseph L. Shaker, et al.
Published: (2015-09-01)

Uterine fibroids – what’s new? [version 1; referees: 3 approved]
by: Alistair R.W. Williams
Published: (2017-12-01)

Correction: Safety and Immunogenicity of Boosting BCG Vaccinated Subjects with BCG: Comparison with Boosting with a New TB Vaccine, MVA85A
by: Kathryn T. Whelan, et al.
Published: (2011-01-01)

Correction: Safety and Immunogenicity of Boosting BCG Vaccinated Subjects with BCG: Comparison with Boosting with a New TB Vaccine, MVA85A.
by: Kathryn T. Whelan, et al.
Published: (2011-01-01)

Research and development of new tuberculosis vaccines: a review [version 1; referees: 2 approved, 1 approved with reservations]
by: Lewis K. Schrager, et al.
Published: (2018-11-01)

Research and development of new tuberculosis vaccines: a review [version 2; referees: 3 approved, 1 approved with reservations]
by: Lewis K. Schrager, et al.
Published: (2019-02-01)

RNA interactomics: recent advances and remaining challenges [version 1; referees: 2 approved]
by: Brigitte Schönberger, et al.
Published: (2018-11-01)

Provider perspectives on demand creation for maternal vaccines in Kenya [version 1; referees: 2 approved]
by: Irina Bergenfeld, et al.
Published: (2018-07-01)

Lassa virus diversity and feasibility for universal prophylactic vaccine [version 1; referees: 3 approved]
by: Igor S. Lukashevich, et al.
Published: (2019-01-01)

Rotavirus Vaccines: a story of success with challenges ahead [version 1; referees: 3 approved]
by: Miguel O’Ryan
Published: (2017-08-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells [version 1; peer review: 2 approved]
by: Rachel Tanner, et al.
Published: (2021-03-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells [version 2; peer review: 2 approved]
by: Rachel Tanner, et al.
Published: (2021-09-01)

Preclinical development of an in vivo BCG challenge model for testing candidate TB vaccine efficacy.
by: Angela M Minassian, et al.
Published: (2011-01-01)

Lessons from the first clinical trial of a non-licensed vaccine among Ugandan adolescents: a phase II field trial of the tuberculosis candidate vaccine, MVA85A [version 1; referees: 1 approved, 2 approved with reservations]
by: Anne Wajja, et al.
Published: (2018-09-01)

Advances in Laryngoscopy [version 1; referees: 2 approved]
by: Michael Aziz
Published: (2015-12-01)

The mechanism of translation [version 1; referees: 3 approved]
by: Joachim Frank
Published: (2017-03-01)

Ketamine for pain [version 1; referees: 2 approved]
by: Kelly Jonkman, et al.
Published: (2017-09-01)

Hubris and Sciences [version 1; referees: 2 approved]
by: Eleftherios P Diamandis, et al.
Published: (2018-02-01)

Mask ventilation [version 1; referees: 2 approved]
by: Paul Baker
Published: (2018-10-01)

Cancer Genomics [version 1; referees: 2 approved]
by: Elaine Mardis
Published: (2015-10-01)

Cannot write session to /tmp/vufind_sessions/sess_m5d9vggdvf4autepvnh84vs1sq