Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst

An efficient synthesis of (1H-tetrazole-5-yl) pyrazines is achieved by one pot multi- component coupling reaction of α-dicarbonyl compounds, 2,3-diaminomaleonitrile and sodium azide using MgFe2O4 nanoparticles as a robust catalyst under ultrasonic irradiation. This novel synthesic method using MgFe2...

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Main Authors:	Javad Safaei-Ghomi, Soleiman Paymard-Samani, Hossein Shahbazi-Alavi
Format:	Article
Language:	English
Published:	Nanoscience and Nanotechnology Research Center, University of Kashan 2018-10-01
Series:	Journal of Nanostructures
Subjects:	pyrazines mgfe2o4 nanoparticles ultrasonic irradiation heterogeneous catalysts
Online Access:	http://jns.kashanu.ac.ir/article_53528_d1c38270918637ec076de43e3eec781d.pdf

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spelling	doaj-723a41ba4a49461395f5bc65dcf43aa42020-11-25T03:30:12ZengNanoscience and Nanotechnology Research Center, University of KashanJournal of Nanostructures2251-78712251-788X2018-10-018438339010.22052/JNS.2018.04.00853528Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous CatalystJavad Safaei-Ghomi0Soleiman Paymard-Samani1Hossein Shahbazi-Alavi2Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranAn efficient synthesis of (1H-tetrazole-5-yl) pyrazines is achieved by one pot multi- component coupling reaction of α-dicarbonyl compounds, 2,3-diaminomaleonitrile and sodium azide using MgFe2O4 nanoparticles as a robust catalyst under ultrasonic irradiation. This novel synthesic method using MgFe2O4 nanoparticles is easier, faster than that of using other nanoparicles. MgFe2O4 nanoparticles have been characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The attractive advantages of the present process are atom economy, wide range of products, high catalytic activity, excellent yields, short reaction times and simple operational procedures. Use of simple and readily available starting materials, experimental simplicity, applying the sono-chemical methodology as an efficient method and innocuous means of activation in synthetic chemistry are some properties of this protocol. The reusability of the MgFe2O4 nanoparticles catalyst was examined and it was found that product yields decreased to a small extent on each reuse. The possibility of performing multicomponent reactions with a green catalyst under ultrasonic irradiation plays a prominent role in green chemistry.http://jns.kashanu.ac.ir/article_53528_d1c38270918637ec076de43e3eec781d.pdfpyrazinesmgfe2o4 nanoparticlesultrasonic irradiationheterogeneous catalysts
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Javad Safaei-Ghomi Soleiman Paymard-Samani Hossein Shahbazi-Alavi
spellingShingle	Javad Safaei-Ghomi Soleiman Paymard-Samani Hossein Shahbazi-Alavi Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst Journal of Nanostructures pyrazines mgfe2o4 nanoparticles ultrasonic irradiation heterogeneous catalysts
author_facet	Javad Safaei-Ghomi Soleiman Paymard-Samani Hossein Shahbazi-Alavi
author_sort	Javad Safaei-Ghomi
title	Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst
title_short	Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst
title_full	Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst
title_fullStr	Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst
title_full_unstemmed	Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst
title_sort	ultrasonic accelerated efficient synthesis of (1h-tetrazole-5-yl) pyrazines catalyzed by mgfe2o4 nanoparticles as a reusable heterogeneous catalyst
publisher	Nanoscience and Nanotechnology Research Center, University of Kashan
series	Journal of Nanostructures
issn	2251-7871 2251-788X
publishDate	2018-10-01
description	An efficient synthesis of (1H-tetrazole-5-yl) pyrazines is achieved by one pot multi- component coupling reaction of α-dicarbonyl compounds, 2,3-diaminomaleonitrile and sodium azide using MgFe2O4 nanoparticles as a robust catalyst under ultrasonic irradiation. This novel synthesic method using MgFe2O4 nanoparticles is easier, faster than that of using other nanoparicles. MgFe2O4 nanoparticles have been characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The attractive advantages of the present process are atom economy, wide range of products, high catalytic activity, excellent yields, short reaction times and simple operational procedures. Use of simple and readily available starting materials, experimental simplicity, applying the sono-chemical methodology as an efficient method and innocuous means of activation in synthetic chemistry are some properties of this protocol. The reusability of the MgFe2O4 nanoparticles catalyst was examined and it was found that product yields decreased to a small extent on each reuse. The possibility of performing multicomponent reactions with a green catalyst under ultrasonic irradiation plays a prominent role in green chemistry.
topic	pyrazines mgfe2o4 nanoparticles ultrasonic irradiation heterogeneous catalysts
url	http://jns.kashanu.ac.ir/article_53528_d1c38270918637ec076de43e3eec781d.pdf
work_keys_str_mv	AT javadsafaeighomi ultrasonicacceleratedefficientsynthesisof1htetrazole5ylpyrazinescatalyzedbymgfe2o4nanoparticlesasareusableheterogeneouscatalyst AT soleimanpaymardsamani ultrasonicacceleratedefficientsynthesisof1htetrazole5ylpyrazinescatalyzedbymgfe2o4nanoparticlesasareusableheterogeneouscatalyst AT hosseinshahbazialavi ultrasonicacceleratedefficientsynthesisof1htetrazole5ylpyrazinescatalyzedbymgfe2o4nanoparticlesasareusableheterogeneouscatalyst
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Ultrasonic Accelerated Efficient Synthesis of (1H-tetrazole-5-yl) Pyrazines Catalyzed by MgFe2O4 Nanoparticles as a Reusable Heterogeneous Catalyst

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